Much noticed,
much cited
advanceCOR is a company with strong research capabilities. Our scientists regularly publish their results in renowned scientific journals.
2023
Flow chamber staining modality for real-time inspection of dynamic phenotypes in multiple histological stains 2022
Zhongmin Li, Goetz Muench, Silvia Goebel, Kerstin Uhland, Clara Wenhart, Andreas Reimann. Published: May 4, 2023. Get the PDF
Learn moreMinimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets
Han C, Ren P, Mamtimin M, Kruk L, Sarukhanyan E, Li C, Anders HJ, Dandekar T, Krueger I, Elvers M, Goebel S, Adler K, Münch G, Gudermann T, Braun A, Mammadova-Bach E. Biomedicines. Get the PDF
Learn morePlasma Soluble Glycoprotein VI, Platelet Function, Bleeding, and Ischemic Events in Patients Undergoing Elective Percutaneous Coronary Intervention
Shqipdona Lahu, Kristin Adler, Katharina Mayer, Ralph Hein-Rothweiler, Isabell Bernlochner, Gjin Ndrepepa, Stefanie Schüpke, Stefan Holdenrieder, Dario Bongiovanni, Karl-Ludwig Laugwitz, Heribert Schunkert, Meinrad Gawaz, Steffen Massberg, Adnan Kastrati, Götz Münch
DOI https://doi.org/10.1055/s-0043-1772221.
Learn more2022
The Novel Antiplatelet Agent Revacept in Cardiovascular Medicine: The Promise of Efficacy Without Bleeding
Contursi A, Ballerini P, Alberti S, Münch G, Patrignani P. Get the PDF
Learn moreDefinition of a sectioning plane and place for a section containing hoped‑for regions using a spare counterpart specimen
Zhongmin Li, Goetz Muench, Clara Wenhart, Silvia Goebel & Andreas Reimann. Nature/Scientifc Reports 12, Article number: 13342 (2022). Get the PDF
Learn moreRevacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Multicenter Randomized Phase II Trial
Uphaus T; Richards T; Weimar C; Neugebauer H; Poli S; Weissenborn K; Imray C; Michalski D; Rashid H; Loftus I; Rummey C; Ritter M; Hauser T-K; Münch G; Gröschel K; Poppert H. Get the PDF
Learn more2021
Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial
Mayer K, Hein-Rothweiler R, Schüpke S, et al. for the ISAR-Plaster investigators. Get the PDF - Get the Supplemental Online Content
Learn moreTissue block staining and domestic adhesive tape yield qualified integral sections of adult mouse orbits and eyeballs
Zhongmin Li, Martin Ungerer, Julia Faßbender, Clara Wenhart, Hans-Peter Holthoff, Goetz Muench. PLOS ONE. Get the PDF
Learn moreA fructosylated peptide derived from a collagen II T cell epitope for long‑term treatment of arthritis (FIA‑CIA) in mice
Clara Wenhart, Hans‑Peter Holthof, Andreas Reimann, Li Zhongmin, Julia Faßbender, Martin Ungerer. Nature/Scientifc Reports 2021 11:17345. Get the PDF
Learn more2020
Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Artery Stenosis: Design and Rationale of a Randomized Phase II Clinical Trial
Gröschel K, Uphaus T, Loftus I., Poppert H, Diener HC, Zobel J, Münch G. Volume 04, Number 04 of TH Open. Get the PDF
Learn moreThyroid-stimulating hormone receptor (TSHR) fusion proteins in Graves’ disease
Hans-Peter Holthoff, Kerstin Uhland, Gabor Laszlo Kovacs, Andreas Reimann, Kristin Adler, Clara Wenhart and Martin Ungerer. Journal of Endocrinology (2020) 246, 135–147. Get the PDF
Learn moreThe antiplatelet agent revacept prevents the increase of systemic thromboxane A2 biosynthesis and neointima hyperplasia
Sara Alberti, Qianqian Zhang, Ilaria D’Agostino, Annalisa Bruno, StefaniaTacconelli, Annalisa Contursi, Simone Guarnieri , Melania Dovizio, Lorenza Falcone , Patrizia Ballerini, Götz Münch , YingYu & Paola Patrignani. Nature Research Scientifc Reports. Get the PDF
Learn more2019
The Scavenger Receptor CD68 Regulates Platelet Mediated Oxidized Low-Density Lipoprotein (oxLDL) Deposition in Atherosclerotic Vessels at an Early Stage of Atherosclerosis in LDLR-/-/ApoBec-/- Mice
Zeibig S, Büttcher M, Goebel S, Pauli J, Hunger A, Ungerer M, Gawaz M Münch G. Cell Physiol Biochem 2019;52;681-695. Get the PDF
Learn moreTherapeutic Effects of Short Cyclic and Combined Epitope Peptides in a Long-Term Model of Graves’ Disease and Orbitopathy
Faßbender J, Holthoff HP, Li Z, Ungerer M. THYROID Volume 29, Number 2, 2019. Get the PDF
Learn more2018
Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure
Boivin-Jahns V, Uhland K, Holthoff H-P,Beyersdorf N, Kocoski V, Kerkau T, Münch G, Lohse M. Ungerer M, Jahns R. PLoS ONE13(8): publ Aug 20, 2018. Get the PDF
Learn more2017
Cyclic Peptides for Effective Treatment in a Long-Term Model of Graves Disease and Orbitopathy in Female Mice
Holthoff HP, Li Z, Faßbender J, Reimann Adler K, Münch G, Ungerer M. Endocrinology 158:1-16, 2017. Get the PDF
Learn moreRecombinant GPVI-Fc added to single or dual antiplatelet therapy in vitro prevents plaque-induced platelet thrombus formation
Mojica Muñoz AK, Jamasbi J, Uhland K, Degen H, Münch G, Ungerer M, Megens R, Weber C, Lorenz R, Brandl R, Siess W. Thromb Haemost. 2017; 117(8):1651-1659.
Learn moreADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions
Degen H, Borst O, Ziegler M, Mojica Munoz AK, Jamasbi J, Walker B, Göbel S, Fassbender J, Adler K, Brandl R, Münch G, Lorenz R, Siess W, Gawaz M, Ungerer M. J Am Heart Ass 2017, 6:e005991; as of July 27, 2017. Get the PDF
Learn more2016
Review of Mouse Models of Graves’ Disease and Orbitopathy—Novel Treatment by Induction of Tolerance
Ungerer M, Faßbender J, Li Z, Münch G, Holthoff HP. Clinic Rev Allerg Immunol /2016-016-8562-7. Get the PDF
Learn moreRabbit models to study atherosclerosis and its complications – Transgenic vascular protein expression in vivo
Baumgartner C, Brandl J, Münch G, , Ungerer M. Progress in Biophysics and Molecular Biology 121 (2016) 131e141.
Learn more2015
Expanding the Roster: Developing New Inhibitors of Intravascular Thrombosis
Kleiman NS; Kolandaivelu K. J Am Coll Cardiol 2015; 65 (22): 2416 – 2419.
Learn moreDifferential Inhibition of Human Atherosclerotic Plaque–Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies
Jamasbi J, Megens RTA, Bianchini M, Münch G, Ungerer M, Faussner A, Sherman S, Walker A, Goyal P, Jung S, Brandl R, Weber C, Lorenz R, Elia N, Farndale J, Siess W. J Am Coll Cardiol 2015; 65 (22): 2404-2415.
Learn moreProlonged TSH Receptor A Subunit Immunization of Female Mice Leads to a Long-Term Model of Graves’ Disease, Tachycardia, and Cardiac Hypertrophy
Holthoff HP, Goebel S, Li Z, Faßbender J,Reimann A, Zeibig S, Lohse M, Münch G, Ungerer M. Endocrinology, April 2015, 156(4):1577–1589. Get the PDF
Learn more2013
Novel antiplatelet drugs in clinical development
Ungerer M, Münch G. Thromb Haemost 2013; 110.
Learn morePharmacological Inhibition of Platelet-Tumor Cell Cross-Talk Prevents Platelet-Induced Overexpression of Cyclooxygenase-2 in HT29 Human Colon Carcinoma Cells
Dovizio M, Maier TH, Alberti S, Di Francesco L, Marcantoni E, Münch G, John C, Suess B, Sgambato A, Steinhilber D, Patrignani P. Mol Pharmacol 84:25–40, July 2013. Get the PDF
Learn moreThe GPVI – Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times
Ungerer M, Li ZM, Baumgartner C, Göbel S, Vogelmann J, Holthoff HP, Bültmann A, Gawaz M, Münch G. PLOS ONE 2013; 8(8):e71193.
Learn moreThe GPVI-Fc Fusion Protein Revacept Improves Cerebral Infarct Volume and Functional Outcome in Stroke
Göbel S, Li ZM, Vogelmann J, Holthoff HP, Degen H, Hermann DM, Gawaz M, Ungerer M, Münch G. PLOS ONE 2013, 8(7):e66960.
Learn more2010 - 2012
The recombinant bifunctional protein aCD133–GPVI promotes repair of the infarcted myocardium in mice
Baumer Y, Leder C, Ziegler M, Schönberger T, Ochmann C, Perk A, Degen H, Schmid-Horch B, Elvers M, Münch G, Ungerer M, Schlosshauer B, Gawaz M. J Thromb Haemost 2012; 10: 1152–64. Get the PDF
Learn moreImpact of glycoprotein VI and platelet adhesion on atherosclerosis—A possible role of fibronectin
Bültmann A, Li Z, Wagner S, Peluso M, Schönberger T, Weis C, Konrad I, Stellos K, Massberg S, Nieswandt B, Gawaz M, Ungerer M, Münch G. J Mol Cell Cardiol 2010; 49(3):532-42.
Learn moreEffect of the oxLDL Binding Protein Fc-CD68 on Plaque Extension and Vulnerability in Atherosclerosis
Zeibig S, Li Z, Wagner S, Holthoff HP, Ungerer M, Bültmann A, Uhland K, Vogelmann J, Simmet T, Gawaz M, Münch G. Circulation Research 2011; 108:695-703.
Learn moreLoss of protease activity of ADAM15 abolishes protective effects on plaque progression in atherosclerosis
Ungerer M, Rosport K, Bültmann A, Piechatzek R, Uhland K, Schlieper P, Gawaz M, Münch G. Int J Cardiol 152_2011 pp. 382-385. Get the PDF
Learn moreNovel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans
Ungerer M, Rosport K, Bültmann A, Piechatzek R, Uhland K, Schlieper P, Gawaz M, Münch G. Circulation 2011; 123: 1891-1899.
Learn moreDetection of Anti β− 1-AR Autoantibodies in Heart Failure by a Cell-Based Competition ELISA
Holthoff HP, Zeibig S, Jahns-Boivin V, Bauer J, Lohse M, Kääb S, Clauss S, Jahns R, Schlipp A, Münch G, Ungerer M. Circulation Research. 2012;111:675–684. Get the PDF
Learn more